08/10/2025 / By S.D. Wells
The gut-brain connection has been a topic of growing scientific interest, and new research from Edith Cowan University in Australia strengthens the case that digestive health and brain health are deeply intertwined.
A large-scale genetic analysis of more than 400,000 people, published in Communications Biology, found that five common gut disorders—gastroesophageal reflux disease (GERD), peptic ulcer disease (PUD), gastritis-duodenitis, irritable bowel syndrome (IBS), and diverticulosis—are genetically linked to Alzheimer’s disease (AD).
Although scientists have long suspected a relationship between gut disorders and Alzheimer’s, this study is the first to clearly demonstrate a shared genetic foundation. Lead researcher Emmanuel Adewuyi, Ph.D., explained that these results reveal “a novel insight into the genetics behind the observed co-occurrence of AD and gut disorders,” offering new opportunities for earlier detection and treatment strategies.
While the findings do not prove that gut conditions cause Alzheimer’s—or vice versa—they highlight the need for a proactive approach to gut health as part of overall cognitive wellness. Both conditions appear to share genetic risk factors, suggesting that vulnerabilities in gut health could also signal brain health risks.
The study reinforces the importance of maintaining a healthy gut to potentially reduce the risk of cognitive decline. Several lifestyle strategies can help:
Nutritional psychiatry pioneer Dr. Drew Ramsey, M.D., underscores the everyday link between gut and brain health through his own grocery list. His science-backed staples include:
The body operates as an interconnected system, meaning gut health can directly influence mental resilience and cognitive longevity. By prioritizing gut-friendly, nutrient-dense foods, maintaining physical activity, and supplementing wisely, you may help protect not just your digestion but also your brain function as you age.
The takeaway from this research is clear: taking care of your gut is more than a digestive concern—it may be one of the most powerful steps you can take for long-term brain health and Alzheimer’s prevention.
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Tagged Under:
Alzheimer's, brain health, brain protection, dementia, dementia causes, Diseases, dopamine, gut dementia, gut health
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